The TV series Agents Of S.H.I.E.L.D. gets a comic... set in the main comics Marvel Universe and introducing Marvel Universe versions of the characters, not their existing Marvel Cinematic Universe versions.
Okay, you have my interest.
(It increases our chances of getting figures, to follow the newly revealed MCU Agents Coulson and Hill figures.)
It’s also a great way to avoid continuity issues with a spinoff for an ongoing series.
What would change from dropping your core cast, almost as-is, into a Slightly Different Universe, perhaps using a different system?