He was a trickster. Ziggy Stardust, Aladdin Sane, The Thin White Duke... The Man Who Fell To Earth, The Goblin King - and in gaming he was Boz of Omikron.
As an adolescent, I was painfully shy, withdrawn. I didn’t really have the nerve to sing my songs on stage and nobody else was doing them. I decided to do them in disguise so that I didn’t have to actually go through the humiliation of going on stage and being myself. I continued designing characters with their own complete personalities and environments. I put them into interviews with me! Rather than be me - which must be incredibly boring to anyone - I’d take Ziggy in, or Aladdin Sane or The Thin White Duke. It was a very strange thing to do.Musician magazine interview, 1983
And in so doing, he helped make a place for outsiders.
And he was very good at keeping a straight face.
A game featuring Bowie himself might draw from his influence on Doctor Who in particular.
Whenever I think up a dangerous and charming character, they might well have a hint of Bowie.